Physical Resilience in Daily Functioning Among Acutely Ill Hospitalized Older Adults: The Hospital-ADL Study

医学 社会心理的 日常生活活动 观察研究 害怕跌倒 前瞻性队列研究 物理疗法 队列研究 功能损害 伤害预防 毒物控制 内科学 急诊医学 精神科
作者
Daisy Kolk,René J. F. Melis,Janet L. MacNeil Vroomen,Bianca M. Buurman,Lucienne A. Reichardt,Jesse J. Aarden,Rosanne van Seben,Marike van der Schaaf,M. van der Esch,Raoul Engelbert,Jos W. R. Twisk,Jos A. Bosch,Ingeborg M.J.A. Kuper,Annemarieke de Jonghe,Maike Leguit-Elberse,Ad Kamper,Nynke Posthuma,Nienke Brendel,Johan Wold
出处
期刊:Journal of the American Medical Directors Association [Elsevier BV]
卷期号:23 (5): 903.e1-903.e12 被引量:15
标识
DOI:10.1016/j.jamda.2021.08.029
摘要

ObjectivesInsight into older adults' physical resilience is needed to predict functional recovery after hospitalization. We assessed functional trajectories in response to acute illness and subsequent hospitalization and investigated baseline variables and dynamic variables associated with these trajectories.DesignProspective observational cohort study (Hospitalization-Associated Disability and impact on daily Life Study).Setting and ParticipantsThis study included 207 older adults (aged 79.8 ± 6.9 years, 49% female, 57% frail) acutely hospitalized in 6 Dutch hospitals.MethodsFunctional disability was assessed using the 15-item modified activities of daily living index retrospectively 2 weeks before admission, and prospectively from admission up to 3 months after discharge. Baseline variables including frailty, somatic, physical, and psychosocial factors were assessed at admission. Dynamic variables (step count, pain, fatigue, and fear of falling) were continuously or repeatedly assessed during hospitalization. We performed individual spline modeling using random effects. Baseline variables and within-person mean levels and variability in the dynamic variables were assessed as predictors of functional trajectories.ResultsFunctional disability significantly increased before admission and decreased from admission to 3 months post discharge. Frail participants had a significantly higher increase in functional disability before admission compared with nonfrail participants. Lower step count, higher pain scores, and higher within-person variability in fear of falling were significantly associated with higher increase in functional disability before admission. Higher within-person variability in fear of falling was associated with more recovery.Conclusions and ImplicationsOlder adults increase in functional disability before hospitalization and start to recover from admission onward. Frailty and dynamic variables are associated with a higher increase in functional disability after acute illness. Our findings give more insight into older adults' physical resilience, which may improve the prediction of functional recovery and may improve therapeutic decision-making and rehabilitation strategies to improve functional recovery after acute hospitalization.
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