小RNA
核糖核酸
肺癌
长非编码RNA
医学
癌症研究
转移
基因
非编码RNA
肺
计算生物学
癌症
生物
遗传学
肿瘤科
内科学
作者
Meng Meng,Jianrong Chen,Jinliang Chen
出处
期刊:Chinese Journal of Asthma
日期:2019-04-20
卷期号:39 (8): 599-602
标识
DOI:10.3760/cma.j.issn.1673-436x.2019.08.008
摘要
Lung cancer is currently the malignant tumor with the highest incidence in the world.Long non-coding RNA (lncRNA) is a RNA transcript with a length more than 200 nucleotides and no protein-coding potential.lncRNA H19, the first identified lncRNA, plays an important regulatory role in tumor proliferation, invasion, and metastasis.This review introduces the biological characteristics of lncRNA H19 and its role in tumors, especially its role and molecular mechanism in lung cancer.
Key words:
Lung neoplasms; Long non-coding RNA H19; MicroRNA; Gene regulation
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