Electrochemical Oxidative Cyclization: Synthesis of Polysubstituted Pyrrole from Enamines

Abstract A conceptually novel method for the preparation of pyrrole is described by electrochemical‐oxidation‐induced intermolecular annulation via enamines. In a simple undivided cell, based on a sodium acetate‐facilitated, polysubstituted pyrrole derivations has been facilely synthesized under external oxidant‐free condition. This electrosynthetic approach providing an environmentally benign protocol for C−C bond cross‐coupling and oxidative annulation, which features unparalleled broad scope of substrates and practicality.