Hidradenitis suppurativa

医学 化脓性汗腺炎 病因学 临床试验 发病机制 生物信息学 皮肤病科 疾病 免疫学 病理 生物
作者
Samantha R. Goldburg,Bruce Strober,Michael Payette
出处
期刊:Journal of The American Academy of Dermatology [Elsevier]
卷期号:82 (5): 1061-1082 被引量:81
标识
DOI:10.1016/j.jaad.2019.08.089
摘要

The treatment of hidradenitis suppurativa (HS) has remained challenging because of the many knowledge gaps regarding etiology. However, recent studies into the pathogenesis of HS have enabled the investigation of newer therapies. The second article in this continuing medical education series reviews the evidence for established therapies for HS, including anti-inflammatories, antibiotics, and surgery. New and emerging therapies that specifically target cytokines involved in HS pathogenesis will be covered. The potential therapeutic roles of anticytokine therapies, including both the expanded application of existing molecules as well as the specific development of novel therapies for HS are discussed. With increased attention on HS and with numerous clinical trials currently underway, we hope that the variety of treatment options for HS will be expanded. The treatment of hidradenitis suppurativa (HS) has remained challenging because of the many knowledge gaps regarding etiology. However, recent studies into the pathogenesis of HS have enabled the investigation of newer therapies. The second article in this continuing medical education series reviews the evidence for established therapies for HS, including anti-inflammatories, antibiotics, and surgery. New and emerging therapies that specifically target cytokines involved in HS pathogenesis will be covered. The potential therapeutic roles of anticytokine therapies, including both the expanded application of existing molecules as well as the specific development of novel therapies for HS are discussed. With increased attention on HS and with numerous clinical trials currently underway, we hope that the variety of treatment options for HS will be expanded. Journal Based CME Instructions and InformationJournal of the American Academy of DermatologyVol. 82Issue 5Preview Full-Text PDF CME examinationJournal of the American Academy of DermatologyVol. 82Issue 5Preview Full-Text PDF
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