A retrospective review of complication rates of Ommaya reservoir placement for intrathecal medication administration.

e18532 Background: Intraventricular devices such as Ommaya reservoirs play a central role in the management of neuro-oncologic diseases. These devices are implanted under the scalp and are used to rapidly administer therapeutic agents into the cerebral ventricles. Despite their routine use, the placement of these devices can be associated with significant morbidity and mortality. In this study we aimed to recognize the different rates of complications from a large single institution database. Methods: We conducted a retrospective analysis of 936 patients who underwent insertion of a vascular device at the University of Florida between 1/2011 and 12/2016. Of those, 22 had placement of an Ommaya reservoir. Clinical data was obtained through a detailed review of electronic medical records, examining complications during the procedure and at several 6-month intervals during the post-operative period. Patients were grouped according to each interval. All data was stored in a HIPAA compliant online database and all collection protocols underwent approval by the local IRB. Results: The patients' age ranged at time of placement from 0 to 78. Out of 22 patients, 13 devices were placed for intrathecal chemotherapy and 11 for hydrocephalus. No patients died as a direct complication of placement. Two patients (9.1%) had a catheter obstruction complication during Ommaya placement. From discharge to 6 months post-op, 1 patient out of 16 (6.3%) had a catheter obstruction, and 4 (25%) had a catheter-related infection. From 6 months to 1 year post-op, 1 patient out of 13 (7.7%) had a catheter obstruction. After 1 year post-op, 1 patient out of 11 (9.1%) had a catheter obstruction and 1 (9.1%) had a ventricular hemorrhage. Conclusions: This study identified catheter-related infection and catheter migration as the most common complications of Ommaya reservoir placement during the post-operative period. Catheter obstruction was the most common complication during the surgical placement. Surgeons and clinicians should take these factors into account when caring for this patient population. Additional studies should be conducted to further analyze these factors and the possible benefits of prophylactic therapy.