马拉特1
基因敲除
下调和上调
小RNA
癌症研究
细胞凋亡
长非编码RNA
MTT法
细胞生长
生物
流式细胞术
化学
分子生物学
基因
生物化学
作者
Zheng-Bin Zhao,Fei Chen,Xiao-Fang Bai
标识
DOI:10.3349/ymj.2019.60.8.727
摘要
Hepatocellular carcinoma (HCC) is a common cancer worldwide. Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), a long noncoding RNA (lncRNA), has been reported to be aberrantly expressed in hypoxic cancer cells. MALAT1 plays a significant role in many malignancies, including HCC. The aim of this study was to explore the role of MALAT1 in hypoxic HCC cells and its underlying regulatory mechanism.
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