Clinical Review on Sensitive Skin: History, Epidemiology, Pathogenesis and Management

Sensitive skin syndrome is a common and important clinical condition not only to the dermatologists but also to the skin care products and cosmetic manufacturing industries. The perception of distressing sensory symptoms like pain and itch are translated to the brain through abrupt neuronal depolarization sometimes in normal circumstances without any signs. Previously only regarded as an over reactive skin to cosmetics and toiletries, sensitive skin gained increasing attention as a syndrome of aberrancy of the nervous system of the skin and the epidermal keratinocytes. The following is a review on the history, epidemiology, pathogenesis and management of the condition.