医学
体外膜肺氧合
体外循环
心源性休克
生命维持
体外
重症监护医学
氧合器
临床试验
体外循环
心脏病学
内科学
心肌梗塞
作者
Hoong Sern Lim,Neil Howell,Aaron M. Ranasinghe
标识
DOI:10.1016/j.cardfail.2016.10.012
摘要
Extracorporeal life support (ECLS) describes a system that involves drainage from the venous circulation and return via an oxygenator into the arterial circulation (veno-arterial extracorporeal membrane oxygenation). ECLS provides effective cardiopulmonary support, but the parallel circulation has complex effects on the systemic and pulmonary circulatory physiology. An understanding of the physiological changes is fundamental to the management of ECLS. In this review, the key physiological concepts and the implications on the clinical management of ECLS are discussed. In addition, the clinical outcomes associated with ECLS in cardiogenic shock are systematically reviewed. The paucity of clinical trials on ECLS highlights the need for randomized trials to guide the selection of patients.
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