A new biphenyl derivative from the mangrove endophytic fungus Phomopsis longicolla HL-2232

A new biphenyl derivative 5,5′-dimethoxybiphenyl-2,2′-diol (1), together with five known compounds (2–5), was isolated from the mangrove endophytic fungus Phomopsis longicolla HL-2232. The structures of these compounds were elucidated using comprehensive spectroscopic methods. The absolute configuration of 4 was determined by single-crystal X-ray diffraction for the first time. The inhibitory activities of all compounds against two Vibrio bacteria were evaluated.