Intermittent Use of Flash Glucose Monitoring Improves Glycemic Control in Chinese Older Patients with Type 2 Diabetes Mellitus

血糖性 医学 内科学 2型糖尿病 子群分析 糖尿病 2型糖尿病 观察研究 前瞻性队列研究 胰岛素 内分泌学 置信区间
作者
Yonghui Hu,Rengna Yan,Yun Shen,Huiqin Li,Jianhua Ma,Xiaofei Su
出处
期刊:Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy [Dove Medical Press]
卷期号:Volume 18: 1-9
标识
DOI:10.2147/dmso.s498620
摘要

Objective: To explore the efficacy and safety of intermittent use of flash glucose monitoring (FGM) for improving glycemic control in Chinese elderly patients with type 2 diabetes mellitus (T2DM). Methods: This is a prospective observational study involving patients with T2DM aged ≥ 60 years. The study period spans 12 weeks, with participants wearing FGM at weeks 0, 5, and 10. Participants were divided into two subgroups based on HbA1c at enrollment: < 7.0% and ≥ 7.0%. The primary outcome of the study was HbA1c level. Secondary outcomes included time in range (3.9– 10mmol/L) (TIR), time below range (< 3.9mmol/L) (TBR), time above range (> 10.0mmol/L) (TAR), and glycemic variability (GV). Results: A total of 68 patients completed the 12-week FGM follow-up (age 67.9 ± 5.2 years; BMI 25.4 ± 3.3kg/m²). Overall findings revealed that compared to baseline, HbA1c decreased from 7.81 ± 1.25% to 7.44± 1.10% after 12 weeks of intermittent wearing of FGM (p < 0.001). In the subgroup analysis with HbA1c ≥ 7.0%, the results showed a significant reduction in HbA1c of 0.51mmol/L after 12 weeks (8.36 ± 0.95% vs 7.75 ± 0.97%, p < 0.001). And there was a significant reduction in TBR in the subgroup with HbA1c < 7% (p = 0.028). Multiple linear regression analysis showed that the baseline HbA1c (β = − 0.529, P< 0.001), duration of T2DM (β = 0.341, P = 0.001), and the frequency of sensor use (β = − 0.269, P = 0.043) were associated with the reduction in HbA1c level. Conclusion: Intermittent use of FGM is associated with an improvement in glycemic outcomes and reduces the risk of hypoglycemia in Chinese elderly patients with T2DM. Keywords: flash glucose monitoring, type 2 diabetes mellitus, HbA1c, time in range
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
陈隆完成签到,获得积分10
1秒前
1秒前
高乾飞完成签到 ,获得积分10
2秒前
河大青椒完成签到,获得积分10
2秒前
丘比特应助动听的秋白采纳,获得10
3秒前
晒黑的雪碧完成签到,获得积分10
4秒前
yao chen完成签到,获得积分10
5秒前
catch完成签到,获得积分10
5秒前
Hrx完成签到,获得积分10
5秒前
哎呀哎呀25完成签到,获得积分10
6秒前
9秒前
Shark完成签到 ,获得积分10
9秒前
我要发财完成签到,获得积分10
10秒前
卡卡罗特完成签到,获得积分10
10秒前
10秒前
天天向上完成签到 ,获得积分10
11秒前
Xinxxx完成签到,获得积分10
11秒前
Echoheart完成签到,获得积分10
11秒前
Hrx发布了新的文献求助10
12秒前
我要发财发布了新的文献求助10
14秒前
WJing发布了新的文献求助10
15秒前
haonanchen完成签到,获得积分10
16秒前
彭于晏应助专注的白柏采纳,获得10
16秒前
99v587完成签到,获得积分10
17秒前
愤怒的小马发布了新的文献求助200
18秒前
朴素海亦完成签到 ,获得积分10
19秒前
wishes完成签到 ,获得积分10
20秒前
20秒前
南城完成签到 ,获得积分10
21秒前
21秒前
23秒前
Andy完成签到,获得积分10
25秒前
伦语发布了新的文献求助10
25秒前
xdc发布了新的文献求助10
27秒前
zoe发布了新的文献求助10
29秒前
ccCherub完成签到,获得积分10
31秒前
霍楠完成签到,获得积分10
31秒前
星辰大海应助rainny采纳,获得10
31秒前
EZ完成签到 ,获得积分10
31秒前
谨慎翎完成签到 ,获得积分10
32秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Handbook of Industrial Diamonds.Vol2 1100
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038368
求助须知:如何正确求助?哪些是违规求助? 3576068
关于积分的说明 11374313
捐赠科研通 3305780
什么是DOI,文献DOI怎么找? 1819322
邀请新用户注册赠送积分活动 892672
科研通“疑难数据库(出版商)”最低求助积分说明 815029