细胞毒性T细胞
内生
CD8型
免疫学
免疫
T细胞
癌症研究
抗原
医学
生物
免疫系统
遗传学
内科学
体外
作者
X. Li,Feifei Wang,Kun Chen,Zhiyuan Wu,Ruochan Zhang,Chunying Xiao,Fei Zhao,Dongmei Wang,Hong Zhao,Yuliang Ran,Chunfeng Qu
标识
DOI:10.1136/jitc-2024-010581
摘要
Treatment with CEA-specific, XCL1-secreting CAR-T cells for CEA-positive tumors promoted the generation of CD8+ T cells against tumor neoantigens, mediating a long-term antitumor immunity against heterogeneous CRCs.
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