A review of liquid crystal monomers: Environmental occurrence, degradation, toxicity, and human exposure of an emerging class of E-waste pollutants

Liquid crystal monomers (LCMs) are a class of organic compounds with diphenyl or dicyclohexane as the skeleton structure, which are widely used in the manufacturing of liquid crystal displays. They are recognized as novel organic compounds with persistence, bioaccumulation, toxicity, and potential for long-range transport. LCMs are inevitably released into the environment throughout the life cycle of electronic products, and their presence has been found in various abiotic matrixes (air, dust, sediment, leachate, soil) and biotic matrixes (aquatic organisms, human serum, and human skin wipe). Given that studies on LCMs are still in their infancy, this review comprehensively summarizes the extensive literature data on LCMs and identifies key knowledge gaps and future research needs. The physicochemical properties, production, and usage of LCMs are described. Their environmental distribution, degradation, toxicity, and human exposure are also discussed based on the available data and results. Existing data show that LCMs have large-scale environmental pollution and may pose potential ecological and health risks, but it is still insufficient to accurately assess their risks due to the lack of knowledge on LCMs in many areas, such as global contamination trend, environmental behavior, toxic effects, and human exposure assessment. We believe that future studies of LCMs need to investigate LCMs pollution on a large geographic scale, explore their sources, behavior, and fate in the environment, and assess their potential health hazards to organisms and humans.