肺动脉高压
医学
心脏病学
内科学
肺
肺弥散量
扩散能力
肺功能测试
间质性肺病
后负荷
动脉血
呼吸系统
血流动力学
肺功能
作者
Karen M. Olsson,Jan Fuge,Da‐Hee Park,Jan C. Kamp,Torben Brod,Britta Harrigfeld,Jonas C. Schupp,Marius M. Hoeper
出处
期刊:The European respiratory journal
[European Respiratory Society]
日期:2023-07-20
卷期号:62 (2): 2301070-2301070
被引量:2
标识
DOI:10.1183/13993003.01070-2023
摘要
Pulmonary arterial hypertension (PAH) is a rare disease characterised by remodelling of small pulmonary vessels, which results in a progressive increase in right ventricular afterload [1]. Most of the symptoms and signs of PAH are attributable to impaired right heart function. However, patients with PAH also show variable alterations of their lung diffusion capacity for carbon monoxide ( D LCO) and gas exchange, which contribute to disease symptoms and severity. Sotatercept may improve lung diffusion capacity for carbon monoxide and oxygenation in patients with pulmonary arterial hypertension We are indebted to Susanne Tayler, Nicole Wintzenburg, Franziska Zetzsche, and Nicole Shearman (all from the Department of Respiratory Medicine and Infectious Diseases, Hannover Medical School, Hannover, Germany) for their invaluable support during the studies.
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