恶病质
癌症恶病质
医学
癌症
癌症治疗
脂解
生活质量(医疗保健)
内科学
生物信息学
肿瘤科
重症监护医学
脂肪组织
生物
护理部
作者
Kenichi Nishie,Tomomi Nishie,Seiichi Sato,Masayuki Hanaoka
标识
DOI:10.1016/j.drudis.2023.103689
摘要
Cancer cachexia is a complex multifaceted syndrome involving functional impairment and changes in body composition that cannot be reversed by nutritional support. Cancer cachexia is characterized by decreased skeletal muscle mass, increased lipolysis, and decreased food intake. Cancer cachexia decreases chemotherapy tolerance as well as quality of life. However, because no fully effective interventions are available, cancer cachexia remains an unmet need in cancer treatment. In recent years, several discoveries and treatments for cancer cachexia have been studied, and guidelines have been published. We believe that the development of effective strategies for the diagnosis and treatment of cancer cachexia will lead to breakthroughs in cancer treatment.
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