Recent Advances and Applications of Ionic covalent organic frameworks in Food Analysis

Ionic covalent organic frameworks with both crystallinity and charged sites have attracted significant attention from the scientific community. The versatile textural structures, precisely defined channels, and abundant charged sites of ionic COFs offer immense potential in various areas such as separation, sample pretreatment, ion conduction mechanisms, sensing applications, catalytic reactions, and energy storage systems. This review presents a comprehensive overview of facile preparation methods for ionic covalent organic frameworks (iCOFs), along with their applications in food sample pretreatment techniques such as solid-phase extraction (SPE), magnetic solid-phase extraction (MSPE), and dispersive solid-phase extraction (DSPE). Furthermore, it highlights the extensive utilization of iCOFs in detecting various food contaminants including pesticides, contaminants from food packaging, veterinary drugs, perfluoroalkyl substances, and poly-fluoroalkyl substances. Specifically, this review critically discusses the limitations, challenges, and future prospects associated with employing iCOF materials to ensure food safety.