卵巢癌
失调
癌变
阴道癌
癌症
妇科癌症
医学
阴道菌群
肿瘤科
生物信息学
内科学
生物
妇科
肠道菌群
宫颈癌
免疫学
细菌性阴道病
作者
Xiumiao Zhao,Zhaoxia Liu,Tingtao Chen
出处
期刊:Pharmaceutics
[MDPI AG]
日期:2023-03-15
卷期号:15 (3): 948-948
被引量:8
标识
DOI:10.3390/pharmaceutics15030948
摘要
Ovarian cancer represents one of the most challenging gynecologic cancers which still has numerous unknowns on the underlying pathogenesis. In addition to the verified contributors such as genomic predisposition and medical history in the carcinogenesis, emerging evidence points out the potential role of vaginal microbiota in ovarian cancer. Recent studies have underlined the presence of vaginal microbial dysbiosis in cancer cases. Increasing research also indicates the potential correlations between vaginal microbes and cancer carcinogenesis, progression and treatment. Currently, compared with other gynecologic cancers, reports on the roles of vaginal microbiota in ovarian cancer remain scarce and fragmentary. Therefore, in this review, we summarize the roles of vaginal microbiota in various gynecologic diseases, particularly focusing on the potential mechanisms and possible applications of vaginal microbiota in ovarian cancer, giving insight into the involvement of vaginal microbiota in gynecologic cancer treatment.
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