表型
癌症研究
信号转导
生物
基因剔除小鼠
化学
医学
细胞生物学
生物化学
基因
作者
Meixiu Jiang,Dan Wang,Ning Su,Weiming Lou,Yinni Chen,Haiyan Yang,Chen Chen,Feiyang Xi,Yuanli Chen,Libin Deng,Xiaoli Tang
标识
DOI:10.1016/j.intimp.2024.111494
摘要
Taken together, our study suggests that tumor cells utilize TRIM65-JAK1/STAT1 axis to inhibit macrophage M1 polarization and promote tumor growth, reveals the role of TRIM65 in TAM-targeting tumor immunotherapy.
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