Health-related quality of life and its influencing factors among lung cancer patients receiving immune checkpoint inhibitors: A cross-sectional study

医学 肺癌 应对(心理学) 社会支持 描述性统计 生活质量(医疗保健) 横断面研究 内科学 多元分析 评定量表 物理疗法 家庭医学 临床心理学 护理部 病理 心理学 发展心理学 统计 数学 心理治疗师
作者
Hong Wang,Dong Yan,Tiantian Fan,Siying Zhu,Ying Zhou,Yalan Song,Shan Pan,Qiujuan Wu,Yumei Li,Yuan Han
出处
期刊:European Journal of Oncology Nursing [Elsevier BV]
卷期号:68: 102507-102507 被引量:5
标识
DOI:10.1016/j.ejon.2024.102507
摘要

Abstract

Purpose

The aim of this study was to examine the level of health-related quality of life (HRQOL) of lung cancer patients receiving immune checkpoint inhibitors (ICIs) and analyze its influencing factors.

Method

A cross-sectional study was conducted. From April 2022 to March 2023, 560 lung cancer patients receiving ICIs at three medical bases in Guangzhou, China were recruited using a convenient sampling method. A general information questionnaire, the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30), the Social Support Rating Scale (SSRS) and the Medical Coping Modes Questionnaire (MCMQ) were used for collecting data on sociodemographic and clinical characteristics, HRQOL, social support and medical coping mode. A descriptive analysis was conducted to describe HRQOL. Multiple regression analysis was applied to determine the factors influencing HRQOL.

Results

For lung cancer patients receiving ICIs, the mean score of HRQOL was 59.21 ± 19.86. Multivariate analysis indicated that acceptance-resignation coping mode (β = −0.37, P < 0.01), Eastern Cooperative Oncology Group (ECOG) score (β = −0.35, P < 0.01), combination of chemotherapy and/or bevacizumab (β = −0.14, P < 0.01), and subjective support (β = 0.07, P = 0.04) all contributed to 42.7% of the variance in HRQOL of the patients receiving ICIs.

Conclusions

It is imperative to address and resolve the HRQOL issue for lung cancer patients receiving ICIs. The findings suggest nurse practitioners should be aware of a variety of factors that influence HRQOL and provide tailored inventions to patients as early as possible to help them achieve better HRQOL.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
领导范儿应助Nozomi采纳,获得10
1秒前
小马甲应助YJ888采纳,获得10
1秒前
香蕉觅云应助jialiu采纳,获得10
1秒前
cosmos完成签到,获得积分10
2秒前
大个应助独特乘云采纳,获得10
3秒前
3秒前
小晓发布了新的文献求助10
3秒前
wonder123发布了新的文献求助10
5秒前
老实起哞完成签到,获得积分10
5秒前
7秒前
8秒前
gsj发布了新的文献求助10
9秒前
10秒前
所所应助wonder123采纳,获得10
10秒前
11秒前
11秒前
11秒前
田様应助忆茶戏采纳,获得10
11秒前
wss完成签到,获得积分10
12秒前
12秒前
12秒前
song_song发布了新的文献求助10
13秒前
桐桐应助贪玩的野狍子采纳,获得50
13秒前
路小黑发布了新的文献求助10
14秒前
wss发布了新的文献求助10
14秒前
UsihaGuwalgiya完成签到,获得积分10
15秒前
15秒前
16秒前
独特乘云发布了新的文献求助10
16秒前
17秒前
yyyyxxxg完成签到,获得积分10
18秒前
19秒前
健壮的花生zzz完成签到,获得积分10
20秒前
20秒前
Michael-布莱恩特完成签到,获得积分10
21秒前
323431完成签到,获得积分10
22秒前
烟花应助郭小宝采纳,获得10
22秒前
lzx发布了新的文献求助10
23秒前
LJF完成签到,获得积分10
24秒前
量子星尘发布了新的文献求助10
24秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989444
求助须知:如何正确求助?哪些是违规求助? 3531531
关于积分的说明 11254250
捐赠科研通 3270191
什么是DOI,文献DOI怎么找? 1804901
邀请新用户注册赠送积分活动 882105
科研通“疑难数据库(出版商)”最低求助积分说明 809174