Electrochemical Ruthenium-Catalyzed Annulation of Benzamidines Hydrochloride and Internal Alkynes: A Sustainable Route to 1-Aminoisoquinolines

A novel electrochemical process for the synthesis of 1-aminoisoquinoline derivatives through the Ru(III)-catalyzed annulation of benzamidines hydrochloride with alkynes is herein reported. This method eliminates the need for stoichiometric amounts...