Left bundle branch area pacing improving the left atrial outcomes in pace‐dependent patients compared with right ventricular outflow tract septal pacing

医学 心脏病学 内科学 心房颤动 心室流出道 QRS波群 左束支阻滞 前瞻性队列研究 射血分数 心力衰竭
作者
Yanlei Zhao,Qian Liu,Jinglan Wu,Yan Zhang,Ling You,Ruiqin Xie
出处
期刊:Clinical Cardiology [Wiley]
卷期号:47 (2) 被引量:3
标识
DOI:10.1002/clc.24185
摘要

Abstract Background Recent studies suggested that the left bundle branch area pacing (LBBAP) has a better efficacy to reduce QRS duration and produce a lower pacing threshold than the conventional right ventricular outflow tract septal pacing (RVOP), which resulted in a better cardiac function and ventricular synchronization. However, whether the LBBAP has a better efficacy in improving left atrial structure, function in pace‐dependent patients compared with RVOP has not been well studied. Objective The purpose of this study was to compare the atrial outcomes of pace‐dependent patients who received LBBAP or RVOP procedures. Methods and Results A total of 72 patients (including II° AVB, high AVB, and III° AVB, excluding atrial fibrillation patients with atrioventricular block) consecutively enrolled in this single‐center prospective clinical study and randomly assigned to the RVOP group and the LBBP group with 36 patients. All patients were pace‐dependent. The changes in echocardiogram, speckle‐tracking echocardiography, brain natriuretic peptide (BNP), and 6‐min walking distance were documented and compared between two groups at baseline, 7 days, 1, 3, and 6 months after the implantation. There were no significant differences in baseline characteristics between the two groups. The results of the study were as following: (1) left atrial structure index: Our study indicated that there are no significant differences in left atrial anteroposterior dimension (LAAPD), left atrial superoinferior dimension, and left atrial mediolateral dimension between two groups. While the LAAPD in the LBBAP group was significantly reduced at 6 months after implantation ([38.22 ± 2.17] mm vs. [34.13 ± 1.59] mm, p < .05). (2) Left atrial strain index: We observed that the S% was significantly improved in both groups at 3 and 6 months after implantation but more prominent in the LBBAP group at 6 months (36.94 ± 11.67 vs. 25.87 ± 8.93, p = .01). SRs, SRe were improved in the RVOP group at 6 months after implantation but was further significantly increased in the LBBAP group. Similarly, the SRa in the LBBAP group was significantly better than the RVOP group after 6 months (−2.11 ± 0.75 vs. −2.51 ± 0.70, p = .04). (3) Left atrial ejection index: LAEF% in the LBBAP group was significantly improved compared with the RVOP group (60.02 ± 1.88 vs. 53.65 ± 2.45, p = .047) and baseline (60.02 ± 1.88 vs. 49.68 ± 2.75, p < .05) at 6 months after the surgery. (4) Left ventricular ejection index: The LVEF% in the LBBAP group was significantly increased than the RVOP group after 6 months (69.14 ± 4.99 vs. 64.60 ± 4.84, p = .01) and the BNP level was significantly lower in the LBBAP group compared with the RVOP group at 7 days, 1, 3, and 6 months after implantation ( p < .05). (5) 6‐min walking distance: the 6‐min walking distance was significantly increased at 3 and 6 months after implantation compared with that before ( p < .05) in both groups, but was more prominent in LBBAP groups ([483.03 ± 11.02] m vs. [431.09 ± 10.69] m, p < .05). Conclusion Compared with the traditional RVOP, the LBBAP procedure increased left atrial myocardial stress as well as left atrial ejection in pace‐dependent patients at follow‐up to 6 months.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
zimablue完成签到,获得积分10
刚刚
慕青应助范先生采纳,获得10
刚刚
zzz完成签到,获得积分10
1秒前
2秒前
海盗船长完成签到,获得积分10
2秒前
等待寄云完成签到 ,获得积分10
2秒前
酷波er应助王冉冉采纳,获得10
3秒前
lcjynwe完成签到,获得积分10
4秒前
新奇完成签到 ,获得积分10
4秒前
Misty_发布了新的文献求助10
4秒前
iNk应助不会取名字采纳,获得20
4秒前
Orange应助Hannes采纳,获得10
4秒前
6秒前
多多少少忖测的情完成签到,获得积分10
6秒前
小马甲应助lx采纳,获得10
6秒前
7秒前
阔达冰兰发布了新的文献求助10
7秒前
GAO完成签到,获得积分10
7秒前
yy发布了新的文献求助10
8秒前
8秒前
8秒前
奋斗冬萱完成签到,获得积分10
8秒前
康园完成签到,获得积分10
9秒前
活泼的面包完成签到,获得积分10
11秒前
123456完成签到,获得积分10
12秒前
重要谷冬完成签到,获得积分10
12秒前
深情丸子发布了新的文献求助10
12秒前
12秒前
杰瑞完成签到,获得积分10
14秒前
14秒前
ding应助科研通管家采纳,获得10
15秒前
Akim应助科研通管家采纳,获得10
15秒前
领导范儿应助科研通管家采纳,获得10
15秒前
fang应助科研通管家采纳,获得10
15秒前
今后应助科研通管家采纳,获得10
15秒前
李小鑫吖发布了新的文献求助10
15秒前
ding应助科研通管家采纳,获得10
15秒前
搜集达人应助科研通管家采纳,获得10
15秒前
Zoe应助科研通管家采纳,获得50
16秒前
个性元枫应助科研通管家采纳,获得10
16秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
Research on Disturbance Rejection Control Algorithm for Aerial Operation Robots 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038524
求助须知:如何正确求助?哪些是违规求助? 3576221
关于积分的说明 11374737
捐赠科研通 3305912
什么是DOI,文献DOI怎么找? 1819354
邀请新用户注册赠送积分活动 892688
科研通“疑难数据库(出版商)”最低求助积分说明 815048