Pulsed‐field ablation does not induce esophageal and periesophageal injury—A new esophageal safety paradigm in catheter ablation of atrial fibrillation

医学 烧蚀 心房颤动 导管消融 水肿 内科学
作者
Dirk Große Meininghaus,Robert Freund,Britta Koerber,Tobias Kleemann,Harald Matthes,J. Christoph Geller
出处
期刊:Journal of Cardiovascular Electrophysiology [Wiley]
卷期号:35 (1): 86-93 被引量:13
标识
DOI:10.1111/jce.16132
摘要

Abstract Introduction Esophageal injury is one of the most serious complications of pulmonary vein isolation (PVI) with thermic energy sources. Better tissue selectivity of primarily non‐thermic pulsed field ablation (PFA) may eliminate collateral injury, particularly the risk of atrio‐esophageal fistula (AEF). Objective To compare the incidence of any (peri)‐esophageal injury following PVI using PFA to thermic energy sources. Methods Using endoscopy, endoscopic ultrasound, and electrogastrography before and after PVI, esophageal and periesophageal injury (mucosal lesions, food retention, periesophageal edema, or vagal nerve injury) were assessed following PFA and radiofrequency (RF)‐ or cryoballoon (CB)‐PVI. Results Between December 2022 and February 2023, 20 patients (67 ± 10 years, 53% male) undergoing PFA (Farapulse, Boston Scientific) for atrial fibrillation (AF) were studied and compared with a previous cohort of 57 patients who underwent thermic PVI (CB: n = 33; RF: n = 24). Following PFA‐PVI, none of the patients had mucosal lesions, food retention, or ablation‐induced vagal nerve injury; four patients showed periesophageal edema. Following thermic ablation, 33/57 patients (58%) showed esophageal and/or periesophageal injury (CB: 21/33 [64%], RF: 12/24 [50%]), in detail 4/57 mucosal lesions, 18/57 food retention, 17/57 vagal nerve injury, and 20/52 edema. Midterm success rates were similar for all energy sources. Conclusion In contrast to thermic ablation tools, PFA is not associated with relevant esophageal and periesophageal injury, and might, therefore, reduce or eliminate the risk of potentially lethal AEF in interventional treatment of AF. The etiology of ablation‐induced periesophageal edema is unknown but has not been shown to be related to lesion progression.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
3秒前
潇湘雪月发布了新的文献求助10
4秒前
7秒前
酷波er应助hello采纳,获得10
7秒前
7秒前
啦啦发布了新的文献求助10
7秒前
唯美发布了新的文献求助10
11秒前
hnlgdx发布了新的文献求助10
15秒前
一根完成签到,获得积分20
15秒前
七月完成签到 ,获得积分10
17秒前
xiaojiahuo完成签到,获得积分10
18秒前
19秒前
猪猪hero发布了新的文献求助10
19秒前
自信不愁完成签到,获得积分10
20秒前
潇湘雪月发布了新的文献求助10
21秒前
Arthur完成签到,获得积分10
22秒前
22秒前
量子星尘发布了新的文献求助10
23秒前
芋孟齐完成签到,获得积分20
23秒前
猪猪hero发布了新的文献求助10
25秒前
26秒前
高手发布了新的文献求助10
26秒前
26秒前
WN发布了新的文献求助10
26秒前
超级的鹅发布了新的文献求助10
29秒前
FashionBoy应助axin采纳,获得10
30秒前
胡霖完成签到,获得积分10
31秒前
流飒完成签到,获得积分10
31秒前
香蕉觅云应助牛马码字员采纳,获得10
32秒前
猪猪hero发布了新的文献求助10
32秒前
CAOHOU应助林sir采纳,获得10
32秒前
32秒前
甜甜亦巧完成签到,获得积分10
33秒前
栗惠发布了新的文献求助20
34秒前
34秒前
35秒前
37秒前
小二郎应助高手采纳,获得10
37秒前
38秒前
民科王聪发布了新的文献求助10
38秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989242
求助须知:如何正确求助?哪些是违规求助? 3531393
关于积分的说明 11253753
捐赠科研通 3270010
什么是DOI,文献DOI怎么找? 1804868
邀请新用户注册赠送积分活动 882084
科研通“疑难数据库(出版商)”最低求助积分说明 809136