Plaque enhancement predicts recurrence in acute ischemic stroke patients with large artery intracranial atherosclerosis

医学 列线图 狭窄 内科学 冲程(发动机) 混淆 比例危险模型 心脏病学 放射科 机械工程 工程类
作者
Yanying Zhao,Peng Song,Ping‐Yong Feng,Si Yuan,Haoran Wu,Junzhao Cui,Lijuan Liu,Shaoru Zhang,Ruihan Miao,Guo Li,Weihai Xu,Xiaoyun Liu
出处
期刊:Journal of stroke and cerebrovascular diseases [Elsevier BV]
卷期号:32 (12): 107406-107406 被引量:3
标识
DOI:10.1016/j.jstrokecerebrovasdis.2023.107406
摘要

The association between the degree of plaque enhancement and ischemic brain stroke recurrence remains unclear. We aimed to establish models to predict plaque enhancement and stroke recurrence.Seventy-eight participants with acute ischemic brain stroke due to intracranial arterial stenosis were recruited and divided into high enhancement (HE) and non-HE groups. The relationship between imaging characteristics (degree of stenosis, minimal lumen area, intraplaque hemorrhage, and plaque burden) and the degree of plaque contrast enhancement was analyzed. Inflammatory cytokine expression was examined by flow cytometry. Independent predictors of stroke recurrence were investigated via multivariate Cox proportional hazards regression analysis. Nomogram was used to construct a prediction model. Harrell's concordance indices (c-indices) and calibration curves were used to assess the discrimination of the nomogram. A risk prediction nomogram for prognosis was constructed.Thirty-three participants were assigned to the HE group and 45 to the non-HE group. The degree of stenosis and plaque burden in the HE group was higher than that in the non-HE group (P<0.05). Multiple linear regression analysis showed the degree of stenosis was associated with HE (β=0.513; P=0.000). After adjusting for confounding factors, age (HR=1.115; 95%CI=1.034-1.203, P=0.005) and HE plaques (HR=10.457; 95%CI=1.176-93.018; P=0.035) were independent risk factors of stroke recurrence, whereas cytokine levels were not statistically significant between two group.HE of intracranial atherosclerosis plaques is an independent factor for ischemic brain stroke recurrence.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
蒋瑞轩发布了新的文献求助10
刚刚
小鱼儿完成签到,获得积分10
1秒前
旧戏人发布了新的文献求助10
1秒前
shi发布了新的文献求助10
4秒前
4秒前
xiaoliang完成签到,获得积分10
5秒前
5秒前
5秒前
饶丹完成签到,获得积分10
6秒前
轻松的惜芹应助海棠依旧采纳,获得200
6秒前
WSYang完成签到,获得积分10
7秒前
Akim应助shen采纳,获得10
9秒前
9秒前
DT发布了新的文献求助10
10秒前
赖晨靓发布了新的文献求助10
12秒前
酷酷的爆米花完成签到,获得积分10
14秒前
15秒前
17秒前
大个应助小虫采纳,获得10
17秒前
11完成签到,获得积分10
18秒前
18秒前
乐乐应助shi采纳,获得10
19秒前
王祉萱发布了新的文献求助10
20秒前
Avvei完成签到,获得积分10
20秒前
20秒前
路路发布了新的文献求助10
22秒前
英俊的铭应助notsoeasy采纳,获得10
22秒前
Aono完成签到 ,获得积分10
23秒前
研友_VZG7GZ应助11采纳,获得10
23秒前
自由的凛发布了新的文献求助10
24秒前
24秒前
沉默的半凡完成签到,获得积分10
25秒前
海棠依旧给海棠依旧的求助进行了留言
25秒前
26秒前
27秒前
小虫完成签到,获得积分10
28秒前
Deng完成签到,获得积分10
28秒前
28秒前
科目三应助科研通管家采纳,获得10
30秒前
科研通AI2S应助科研通管家采纳,获得10
30秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3976253
求助须知:如何正确求助?哪些是违规求助? 3520405
关于积分的说明 11203301
捐赠科研通 3257028
什么是DOI,文献DOI怎么找? 1798589
邀请新用户注册赠送积分活动 877755
科研通“疑难数据库(出版商)”最低求助积分说明 806521