Plaque enhancement predicts recurrence in acute ischemic stroke patients with large artery intracranial atherosclerosis

医学 列线图 狭窄 内科学 冲程(发动机) 混淆 比例危险模型 心脏病学 放射科 机械工程 工程类
作者
Yanying Zhao,Peng Song,Ping‐Yong Feng,Si Yuan,Haoran Wu,Junzhao Cui,Lijuan Liu,Shaoru Zhang,Ruihan Miao,Guo Li,Weihai Xu,Xiaoyun Liu
出处
期刊:Journal of stroke and cerebrovascular diseases [Elsevier BV]
卷期号:32 (12): 107406-107406 被引量:3
标识
DOI:10.1016/j.jstrokecerebrovasdis.2023.107406
摘要

The association between the degree of plaque enhancement and ischemic brain stroke recurrence remains unclear. We aimed to establish models to predict plaque enhancement and stroke recurrence.Seventy-eight participants with acute ischemic brain stroke due to intracranial arterial stenosis were recruited and divided into high enhancement (HE) and non-HE groups. The relationship between imaging characteristics (degree of stenosis, minimal lumen area, intraplaque hemorrhage, and plaque burden) and the degree of plaque contrast enhancement was analyzed. Inflammatory cytokine expression was examined by flow cytometry. Independent predictors of stroke recurrence were investigated via multivariate Cox proportional hazards regression analysis. Nomogram was used to construct a prediction model. Harrell's concordance indices (c-indices) and calibration curves were used to assess the discrimination of the nomogram. A risk prediction nomogram for prognosis was constructed.Thirty-three participants were assigned to the HE group and 45 to the non-HE group. The degree of stenosis and plaque burden in the HE group was higher than that in the non-HE group (P<0.05). Multiple linear regression analysis showed the degree of stenosis was associated with HE (β=0.513; P=0.000). After adjusting for confounding factors, age (HR=1.115; 95%CI=1.034-1.203, P=0.005) and HE plaques (HR=10.457; 95%CI=1.176-93.018; P=0.035) were independent risk factors of stroke recurrence, whereas cytokine levels were not statistically significant between two group.HE of intracranial atherosclerosis plaques is an independent factor for ischemic brain stroke recurrence.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
SciGPT应助zj采纳,获得10
1秒前
Ava应助阿湫采纳,获得10
1秒前
meng123完成签到,获得积分20
2秒前
x5kyi完成签到,获得积分10
3秒前
爆米花应助肖遥采纳,获得10
4秒前
Xx完成签到,获得积分10
4秒前
4秒前
7秒前
烟里戏完成签到 ,获得积分10
9秒前
shuangfeng1853完成签到 ,获得积分10
9秒前
林子青发布了新的文献求助10
9秒前
10秒前
aa完成签到,获得积分10
10秒前
CXC完成签到,获得积分10
10秒前
12秒前
Zzz发布了新的文献求助10
12秒前
上官若男应助袁凯文采纳,获得10
13秒前
13秒前
褚晣完成签到,获得积分10
13秒前
ATTENTION完成签到,获得积分10
14秒前
14秒前
周欣玙完成签到,获得积分10
14秒前
14秒前
学不懂数学应助as采纳,获得30
14秒前
传奇3应助YiWei采纳,获得10
15秒前
阿湫发布了新的文献求助10
15秒前
why完成签到,获得积分10
15秒前
15秒前
慕青应助Zard采纳,获得10
18秒前
肖遥发布了新的文献求助10
19秒前
19秒前
天气一级棒完成签到,获得积分10
20秒前
TAA66完成签到,获得积分10
20秒前
小凯同学完成签到,获得积分10
20秒前
20秒前
星辰完成签到,获得积分10
23秒前
gomm完成签到,获得积分10
23秒前
星辰大海应助票子采纳,获得10
24秒前
Accpted河豚完成签到,获得积分10
24秒前
苏唱发布了新的文献求助10
24秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
Research on Disturbance Rejection Control Algorithm for Aerial Operation Robots 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038524
求助须知:如何正确求助?哪些是违规求助? 3576221
关于积分的说明 11374737
捐赠科研通 3305912
什么是DOI,文献DOI怎么找? 1819354
邀请新用户注册赠送积分活动 892688
科研通“疑难数据库(出版商)”最低求助积分说明 815048