An ultimate strength analysis of composite beams with unreinforced, rectangular web openings is presented. The analysis is developed for general beam geometry and material properties, and for a single web opening of any practical depth, width and location. The beneficial effects of strain hardening and the shear contribution of the slab are neglected, and a four hinge failure mechanism at the opening is assumed. Analytical results indicate that a composite section with a web opening has a significantly higher bending strength than the corresponding noncomposite section, and that variations in opening length, height and eccentricity can have a significant effect on the ultimate strength. Comparison of the analytical results with the limited experimental data available indicates that the theory provides a very conservative estimate of the ultimate strength. The discrepancy between theory and test results is attributed primarily to strain hardening and the shear contribution of the slab.