妥布霉素
阿米卡星
氨基糖苷
卡那霉素
庆大霉素
微生物学
抗生素
西索米星
人口
化学
生物
医学
环境卫生
作者
Drugeon Hb,Courtieu Al
出处
期刊:PubMed
日期:1979-04-01
卷期号:130A (3): 331-43
被引量:3
摘要
The authors have studied on 20 bacterial strains (5 Pseudomonas aeruginosa, 5 Escherichia coli, 5 Klebsiella and 5 Serratia) the bactericidal kinetics of 4 aminoglycoside antibiotics: amikacin, gentamicin, kanamycin and tobramycin. The antibiotic concentrations used for this work were 1.5 times the MIC for each strain previously measured in a liquid medium. The action of the aminoglycoside antibiotics shows three phases. The third phase describes a part of less susceptible bacterial population. It permits the comparison of the 4 antibiotics. Amikacin shows the best activity, followed by gentamicin, kanamycin and tobramycin.
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