纳米技术
纳米线
硅
材料科学
硅纳米线
灵活性(工程)
从头算
曲率
制作
纳米机电系统
电极
计算机科学
光电子学
纳米颗粒
化学
几何学
有机化学
物理化学
病理
替代医学
统计
医学
数学
纳米医学
作者
Zongguang Liu,Yan Jiang,Haiguang Ma,Tiancheng Hu,Junzhuan Wang,Yi Shi,Jun Xu,Kunji Chen,Linwei Yu
出处
期刊:Nano Letters
[American Chemical Society]
日期:2021-03-17
卷期号:21 (7): 2773-2779
被引量:16
标识
DOI:10.1021/acs.nanolett.0c04804
摘要
Free-standing silicon nanoprobes (SiNPs) are critical tools for intracellular bioelectrical signal recording, while a scalable fabrication of these tiny SiNPs with ab initio geometry designs has not been possible. In this work, we demonstrate a novel growth shaping of slim Si nanowires (SiNWs) into SiNPs with sharp tips (curvature radii <300 nm), tunable angles of 30°, 60°, to 120° and even programmable triangle/circular shapes. A precise growth integration of orderly single, double, and quadruple SiNPs at prescribed locations enables convenient electrode connection, transferring and mounting these tiny tips onto movable arms to serve as long-protruding (over 4–20 μm) nanoprobes. Mechanical flexibility, resilience, and field-effect sensing functionality of the SiNPs were systematically testified in liquid nanodroplet and cell environments. This highly reliable and economic manufacturing of advanced SiNPs holds a strong potential to boost and open up the market implementations of a wide range of intracellular sensing, monitoring, and editing applications.
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