清晨好,您是今天最早来到科研通的研友!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您科研之路漫漫前行!

Patterns and predictors of trajectories for subjective quality of life in patients with early psychosis: Three-year follow-up of the randomized controlled trial on extended early intervention

随机对照试验 生活质量(医疗保健) 背景(考古学) 精神病理学 干预(咨询) 精神病 心理学 心理健康 精神科 医学 临床心理学 内科学 古生物学 心理治疗师 生物
作者
Candice Tze Kwan Kam,Wing Chung Chang,Vivian Wing Yan Kwong,Emily Sin Ki Lau,Gloria Hoi Kei Chan,Olivia Tsz Ting Jim,Christy Lai Ming Hui,Sherry Kit Wa Chan,Edwin Lee,Eric Chen
出处
期刊:Australian and New Zealand Journal of Psychiatry [SAGE Publishing]
卷期号:55 (10): 983-992 被引量:7
标识
DOI:10.1177/00048674211009603
摘要

Objective: Subjective quality of life is an important outcome of psychotic disorders. However, longitudinal course of subjective quality of life in the early illness stage is under-studied. We aimed to investigate the patterns and baseline predictors of subjective quality of life trajectories over 3 years in early psychosis patients, utilizing growth mixing modeling analysis, in the context of a 3-year follow-up of a randomized controlled trial comparing 1-year extension of early intervention with step-down psychiatric care for first-episode psychosis. Method: One hundred sixty Chinese patients were recruited from specialized early intervention program for first-episode psychosis in Hong Kong after they had completed this 2-year early intervention service, and underwent 1-year randomized controlled trial as well as 2-year post–randomized controlled trial follow-up (i.e. 3-year follow-up). Assessments on premorbid adjustment, onset profile, psychopathology, functioning and treatment characteristics were conducted. Individual class membership of subjective quality of life trajectory derived from growth mixing modeling was based on the 36-Item Short Form Health Survey mental component summary scores measured at four different time-points (baseline, 1, 2 and 3 years) among 142 participants across 3-year follow-up. Results: Three distinct subjective quality of life trajectories were identified including higher-improving (68.3%, n = 97), lower-stable (24.6%, n = 35) and deteriorating (7%, n = 10) trajectories. Age of onset; duration of untreated psychosis; depressive, positive and negative symptoms; and intervention condition were significantly different between good (higher-improving trajectory) and poor (combined lower-stable and deteriorating trajectories) trajectory groups. Multiple regression analysis revealed that younger age of onset, more severe depression and receipt of step-down care independently predicted poor subjective quality of life trajectory. Conclusion: Approximately one-third of patients displayed poor subjective quality of life trajectory in the early phase of psychotic illness. Our results affirm depression as a critical determinant of prospective subjective quality of life and underscores positive effect of extended early intervention on sustained subjective quality of life improvement. Further longitudinal research is warranted to facilitate better characterization of subjective quality of life course patterns and development of targeted intervention to optimize subjective quality of life in patients with early psychosis.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
yhgz完成签到,获得积分10
46秒前
不秃燃的小老弟完成签到 ,获得积分10
53秒前
文献搬运工完成签到 ,获得积分10
59秒前
量子星尘发布了新的文献求助10
1分钟前
鲁卓林完成签到,获得积分10
1分钟前
yi完成签到 ,获得积分10
1分钟前
大模型应助科研通管家采纳,获得30
1分钟前
科研通AI2S应助科研通管家采纳,获得10
1分钟前
量子星尘发布了新的文献求助10
3分钟前
若水完成签到 ,获得积分10
3分钟前
3分钟前
喵喵完成签到 ,获得积分10
4分钟前
钱念波完成签到,获得积分10
4分钟前
量子星尘发布了新的文献求助10
4分钟前
4分钟前
Herbs完成签到 ,获得积分10
4分钟前
5分钟前
5分钟前
5分钟前
5分钟前
萝卜猪完成签到,获得积分10
5分钟前
宇文非笑完成签到 ,获得积分10
5分钟前
量子星尘发布了新的文献求助10
6分钟前
6分钟前
6分钟前
mikija完成签到,获得积分20
6分钟前
6分钟前
mikija发布了新的文献求助10
6分钟前
科目三应助我去打球采纳,获得30
6分钟前
6分钟前
我去打球完成签到,获得积分10
6分钟前
从容芮举报端庄的火龙果求助涉嫌违规
6分钟前
我去打球发布了新的文献求助30
6分钟前
7分钟前
7分钟前
微信研友发布了新的文献求助10
7分钟前
玛卡巴卡爱吃饭完成签到 ,获得积分10
7分钟前
量子星尘发布了新的文献求助10
7分钟前
7分钟前
慕青应助科研通管家采纳,获得10
7分钟前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3976683
求助须知:如何正确求助?哪些是违规求助? 3520770
关于积分的说明 11204819
捐赠科研通 3257565
什么是DOI,文献DOI怎么找? 1798733
邀请新用户注册赠送积分活动 877897
科研通“疑难数据库(出版商)”最低求助积分说明 806629