医学
血管造影
心脏病学
心内膜炎
抗血栓
内科学
尸检
外科
放射科
作者
Yuji Tanabe,Tomomi Suzuki,Shingo Kuwata,Yoshihiro Akashi
出处
期刊:PubMed
日期:2022-02-01
卷期号:34 (2): E151-E151
被引量:2
摘要
The current guidelines recommend at least 6 months of antithrombotic and antibiotic prophylaxis following atrial septal occluding device placement using the phrase "until endothelialization." However, neo-endothelialization has not been assessed in vivo in humans. Considering the atrial septal defect occluding device, several autopsy cases and device extraction cases only demonstrated insufficient endothelialization beyond 6 months after implantation caused endocarditis and thrombosis. Accordingly, we have successfully developed a method for determining device endothelialization using angioscopy. This method helped us evaluate the endothelialization of a 25 mm Amplatzer PFO occluder device (Abbott) in a 40-year-old man 12 months after implantation. This is the first report evaluating the PFO occluder device in vivo.
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