Oral lichen planus (OLP) is a chronic and inflammatory oral mucosal disease that commonly affects middle-aged females. Most OLP cases might exhibit such symptom as pain, roughness and other discomfort, and more severe forms may show a high risk of developing oral cancer. Active preventive measure, precise diagnosis and standard therapeutic approach play a vital role in the management and prevention of OLP. This guideline is a revision on the base of trial in 2012, which mainly covers the following 8 aspects: etiology and medical records, clinical manifestations, pathological manifestations, diagnosis, differential diagnosis, laboratory examination, disease treatment and prevention, aiming at providing scientific evidence and guidance for the dental clinicians in diagnose and treatment of OLP.口腔扁平苔藓是一种临床常见的口腔黏膜慢性炎性疾病,以中年女性多见,大多数患者有疼痛、粗糙不适等症状,部分病例还有癌变风险,对患者身心造成较大危害。积极预防、准确诊断和规范治疗对有效防治口腔扁平苔藓具有重要意义。本指南是在2012年试行版基础上进行修订,主要涵盖口腔扁平苔藓的病因及病史采集、临床表现、病理表现、诊断、鉴别诊断、治疗前检查、疾病治疗及预防等8个方面,为该病的临床诊疗提供科学依据和指导。.