植物化学
积雪草
皂甙
油酸烷
皂甙元
传统医学
化学
多酚
植物
生物
三萜
生物化学
抗氧化剂
医学
病理
替代医学
作者
Francesca Masi,Giuseppina Chianese,Federico Peterlongo,Antonella Riva,Orazio Taglialatela‐Scafati
出处
期刊:Fitoterapia
[Elsevier]
日期:2022-02-22
卷期号:158: 105163-105163
被引量:6
标识
DOI:10.1016/j.fitote.2022.105163
摘要
Centella asiatica is a popular medicinal plant and several phytotherapic products in the market include its extracts as active constituents. A LC-MS guided phytochemical investigation on the commercial C. asiatica leaves extract named Centevita® allowed characterization and quantification of 24 secondary metabolites including 10 polyphenols and 14 ursane- or oleanane-type triterpenoids in the sapogenin or saponin form. This metabolomic analysis, besides confirming that the triterpenoid fraction roughly accounts for 45% of the extract weight, also resulted in the discovery of isoterminoloside, a new triglycoside saponin of the unprecedented 2α,3β,6β,23-tetrahydroxyolean-13(18)-en-28-oic acid (isoterminolic acid). The structure of isoterminoloside was characterized by a detailed ESI-MS and NMR investigation.
科研通智能强力驱动
Strongly Powered by AbleSci AI