达布科
化学
双键
药物化学
反应条件
辛烷值
立体化学
组合化学
有机化学
催化作用
作者
Yuhang Xue,Jianbo Gan,Naili Luo,Cunde Wang
标识
DOI:10.1021/acs.joc.2c00869
摘要
DABCO-promoted cyclization reaction of substituted 2-amino-4H-chromen-4-ones with substituted 2,6-dibenzylidenecyclohexan-1-ones was investigated under mild conditions. This reaction provided a novel and efficient access to the 7,8,9,10-tetrahydro-12H-chromeno[2,3-b]quinolin-12-ones in good yields, the exocyclic double bond of which is predominantly E-selective.
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