Cobalt(II)‐Catalyzed C(sp3)−C(sp3) Coupling for the Direct Stereoselective Synthesis of 2‐Deoxy‐C‐Glycosides from Glycals

We report a ligand-controlled CoII -catalyzed C(sp3 )-C(sp3 ) coupling hydroalkylation for direct and β-selective synthesis of 2-deoxy-C-glycosides from glycals. This reaction proceeds by a radical pathway for alkyl halide activation and is β-selective through ligand control. This approach may inspire the development of further stereoselective coupling reactions with potential application in the field of carbohydrates.