脂质代谢
冠心病
发病机制
疾病
脂蛋白
化学
机制(生物学)
生物信息学
医学
内科学
生物化学
生物
胆固醇
哲学
认识论
作者
Jingchun Du,Wei Wu,Boran Zhu,Weiwei Tao,Lina Liu,Xiaolan Cheng,Min Zhao,Jibiao Wu,Yunlun Li,Sicong Tu
标识
DOI:10.1016/j.chemphyslip.2023.105325
摘要
The pathogenesis of coronary heart disease is a highly complex process, with lipid metabolism disorders being closely linked to its development. Therefore, this paper analyzes the various factors that influence lipid metabolism, including obesity, genes, intestinal microflora, and ferroptosis, through a comprehensive review of basic and clinical studies. Additionally, this paper delves deeply into the pathways and patterns of coronary heart disease. Based on these findings, it proposes various intervention pathways and therapeutic methods, such as the regulation of lipoprotein enzymes, lipid metabolites, and lipoprotein regulatory factors, as well as the modulation of intestinal microflora and the inhibition of ferroptosis. Ultimately, this paper aims to offer new ideas for the prevention and treatment of coronary heart disease.
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