作者
Elio Ríboli,Frederick A. Beland,Dirk W. Lachenmeier,M. Matilde Marques,David H. Phillips,Eva Schernhammer,Abdul Afghan,Ricardo Assunção,Giovanna Caderni,J. Christopher Corton,Gisela de Aragão Umbuzeiro,Daphne de Jong,Mélanie Deschasaux,Allison Hodge,Junko Ishihara,Daniel Lévy,Daniele Mandrioli,Marjorie L. McCullough,Sarah A. McNaughton,Takeshi Morita,Anne P. Nugent,Ying‐Chin Ko,Arun R. Pandiri,Consolato Sergi,Mathilde Touvier,Luoping Zhang,Lamia Benbrahim‐Tallaa,Shirisha Chittiboyina,Danila Cuomo,Nathan DeBono,Charlotte Debras,Aline de Conti,Fatiha El Ghissassi,Emma Fontvieille,Rhea Harewood,John Kaldor,Heidelore Fiedler,Elisa Pasqual,Gabrielle Rigutto,Hannah Simba,Eero Suonio,Susana Viegas,Roland Wedekind,Mary K. Schubauer‐Berigan,Federica Madia
摘要
In June, 2023, a Working Group of 25 scientists from 12 countries met at the International Agency for Research on Cancer (IARC) in Lyon, France, to finalise their evaluation of the carcinogenicity of aspartame, methyleugenol, and isoeugenol. Aspartame was classified as "possibly carcinogenic to humans" (Group 2B) based on "limited" evidence for cancer in humans. There was also "limited" evidence for cancer in experimental animals and "limited" mechanistic evidence. Methyleugenol was classified as "probably carcinogenic to humans" (Group 2A) based on "sufficient" evidence for cancer in experimental animals and "strong" mechanistic evidence, including studies in humanised mice and supported by mechanistic studies in exposed humans.