跨细胞
脂质体
外渗
化学
缺氧(环境)
药理学
癌症研究
医学
免疫学
内吞作用
生物化学
受体
有机化学
氧气
作者
Jiajia Su,Chenchen Wu,Jiahui Zou,Xinqiuyue Wang,Kaiyun Yang,Jianping Liu,Zimei Wu,Wenli Zhang
标识
DOI:10.1016/j.jconrel.2024.06.025
摘要
Transcytosis-inducing nanomedicines have been developed to improve tumor extravasation. However, the fate during transcytosis across multicell layers and the structural integrity of the nanomedicines before reaching tumor cells could impact antitumor therapy. Here, a BAY 87-2243 (a hypoxia-inducible factor-1 inhibitor)-loaded liposomal system (HA-P-L
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