化学
级联
光化学
级联反应
组合化学
有机化学
催化作用
色谱法
作者
Julian J. Melder,Maxi L. Heldner,Robin Kugler,Levi A. Ziegenhagen,Frank Röminger,Matthias Rudolph,A. Stephen K. Hashmi
摘要
Herein, the development of a light-mediated synthesis of functionalized indolines and tetrahydroquinolines is reported. These structural motifs are considered as highly valuable targets, attributed to their widespread occurrence in pharmaceuticals and natural products. The gold-mediated approach offers a direct route to functionalized indolines in yields of up to 81% under mild photochemical conditions. Thereby, easily accessible Boc-protected
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