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The prognostic value of HALP score in predicting in-hospital mortality in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention

医学 经皮冠状动脉介入治疗 心肌梗塞 危险系数 内科学 死亡率 回顾性队列研究 人口 背景(考古学) 比例危险模型 心脏病学 外科 置信区间 生物 环境卫生 古生物学
作者
Muammer Karakayalı,Timor Omar,İnanç Artaç,Doğan İliş,Ayça Arslan,Mehmet Altunova,Zihni Çağın,Yavuz Karabağ,Süleyman Karakoyun,İbrahim Rencüzoğulları
出处
期刊:Coronary Artery Disease [Lippincott Williams & Wilkins]
卷期号:34 (7): 483-488 被引量:87
标识
DOI:10.1097/mca.0000000000001271
摘要

Despite major advances in reperfusion therapies, morbidity and mortality rates associated with cardiovascular disorders remain high, particularly in patients with ST-segment elevation myocardial infarction (STEMI). Therefore, identifying prognostic variables that can be used to predict morbidity and mortality in STEMI patients is critical for better disease management. The HALP (hemoglobin, albumin, lymphocyte, and platelet) score, a novel index indicating nutritional status and systemic inflammation, provides information about prognosis. In this context, this study was carried out to investigate the relationship between HALP score assessed at admission and in-hospital mortality in STEMI patients.The population of this retrospective study consisted of 1307 consecutive patients diagnosed with STEMI and who underwent primary percutaneous coronary intervention (pPCI). The 1090 patients included in the study sample were divided into two groups based on the median HALP score value of 3.59. In-hospital and all-cause mortality rates during the follow-up were obtained from the registry.In-hospital mortality rate was significantly higher in patients with a HALP score of less than 3.59 compared to those with a HALP score of more than 3.59 (7.5% and 0.7%, respectively; P < 0.001). Univariate and multivariate Cox proportional hazard analyses revealed that the HALP score is independently associated with in-hospital mortality. The optimal HALP score cutoff value of <3.72 predicted in-hospital mortality with 95.56% sensitivity and 49.19% specificity.This study's findings indicate that HALP score may be a significant independent predictor of in-hospital mortality in patients with STEMI treated with pPCI.
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