免疫疗法
肺癌
癌症
生物
物候学
肿瘤科
表型
生存分析
STK11段
内科学
癌症研究
医学
基因
克拉斯
遗传学
结直肠癌
作者
Stefano Scalera,Biagio Ricciuti,Daniele Marinelli,Marco Mazzotta,Laura Cipriani,Giulia Bon,Giulia Schiavoni,Irene Terrenato,Alessandro Di Federico,Joao V. Alessi,Maurizio Fanciulli,Ludovica Ciuffreda,Francesca De Nicola,Frauke Goeman,Giulio Caravagna,Daniele Santini,Ruggero De Maria,Federico Cappuzzo,Gennaro Ciliberto,Mariam Jamal‐Hanjani
标识
DOI：10.1158/1078-0432.ccr-24-0626
摘要
We identified a KEAPness phenotype across evolutionary divergent tumors. KEAPness outperforms mutation-based classifiers as a biomarker of inferior survival outcomes in patients with NSCLC treated with immunotherapy.
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(2025-6-4)
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