生物
微生物群
杂合子丢失
寄主(生物学)
基因组
进化生物学
脊椎动物
遗传学
系统发育树
遗传多样性
基因
人口
等位基因
人口学
社会学
作者
Iris Holmes,Michael C. Gründler
摘要
Abstract While key elements of fitness in vertebrate animals are impacted by their microbiomes, the host genetic characteristics that factor into microbiome composition are not fully understood. Here, we correlate host genomic heterozygosity and gut microbiome phylogenetic diversity across a community of reptiles in southwestern New Mexico to test hypotheses about the behaviour of host genes that drive microbiome assembly. We find that microbiome communities are phylogenetically under‐dispersed relative to random expectations, and that host heterozygosity is not correlated with microbiome diversity. Our analyses reinforce results from functional genomic work that identify conserved host immune and nonimmune genes as key players in microbiome assembly, rather than gene families that rely on heterozygosity for their function.
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