肝细胞
纤维化
细胞凋亡
细胞生物学
癌症研究
小分子
化学
生物
医学
生物化学
内科学
体外
作者
Ze-Jiang Ma,Ying‐Kun Qiu,Zhe-Wei Yu,Tiantian Song,Yitong Hu,Ankang Peng,Rong Qi
标识
DOI:10.1016/j.jare.2024.12.016
摘要
In conclusion, HO has an inhibitory effect on NASH fibrosis. This effect is mediated by targeting upregulation of hepatocyte FXR, which in turn attenuates hepatocyte apoptosis and thus indirectly inhibits the activation of HSCs.
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