Early breast cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up

Global estimates indicated 2.3 million new cases of breast cancer in 2020, contributing to nearly 12% of all new cancer cases, with 685 000 deaths in the same year.1 Breast cancer detection has increased due to improvements in screening techniques. The mortality rate has decreased in recent years in Western populations, especially in younger age groups,2,3 but breast cancer is still the leading cause of cancer-related deaths for women worldwide. Most early breast cancer (EBC) cases can be cured by multimodality treatment, although cure rates vary by clinical stage and subtype.