Effect of anesthetic strategies on distal stroke thrombectomy in the anterior and posterior cerebral artery

医学 冲程(发动机) 麻醉剂 麻醉 脑动脉 大脑前动脉 大脑后动脉 心脏病学 大脑中动脉 缺血 机械工程 工程类
作者
Lukas Meyer,Christian Paul Stracke,Gabriel Broocks,Marta Wallocha,Mohamed Elsharkawy,Peter B. Sporns,Eike I. Piechowiak,Johannes Kaesmacher,Christian Maegerlein,Moritz Roman Hernandez Petzsche,Hanna Zimmermann,Weis Naziri,Nuran Abdullayev,Christoph Kabbasch,Daniel Behme,Maximilian Thormann,Volker Maus,Sebastian Fischer,Markus Möhlenbruch,Charlotte S. Weyland,Sönke Langner,Marielle Ernst,Ala Jamous,Dan Meila,Milena Miszczuk,Eberhard Siebert,Stephan Lowens,Lars Udo Krause,Leonard L.L. Yeo,Benjamin Yong‐Qiang Tan,Anil Gopinathan,Benjamin Gory,Jorge Galván Fernández,Miguel Schüller Arteaga,Pedro Navía,Eytan Raz,Maksim Shapiro,Fabian Arnberg,Kamil Zeleňák,Mario Martínez‐Galdámez,Maria Eleni Alexandrou,Andreas Kastrup,Panagiotis Papanagiotou,Franziska Dorn,André Kemmling,Marios‐Nikos Psychogios,Tommy Andersson,René Chapot,Jens Fiehler,Uta Hanning
出处
期刊:Journal of NeuroInterventional Surgery [BMJ]
卷期号:16 (3): 230-236 被引量:5
标识
DOI:10.1136/jnis-2023-020210
摘要

Background Numerous questions regarding procedural details of distal stroke thrombectomy remain unanswered. This study assesses the effect of anesthetic strategies on procedural, clinical and safety outcomes following thrombectomy for distal medium vessel occlusions (DMVOs). Methods Patients with isolated DMVO stroke from the TOPMOST registry were analyzed with regard to anesthetic strategies (ie, conscious sedation (CS), local (LA) or general anesthesia (GA)). Occlusions were in the P2/P3 or A2–A4 segments of the posterior and anterior cerebral arteries (PCA and ACA), respectively. The primary endpoint was the rate of complete reperfusion (modified Thrombolysis in Cerebral Infarction score 3) and the secondary endpoint was the rate of modified Rankin Scale score 0–1. Safety endpoints were the occurrence of symptomatic intracranial hemorrhage and mortality. Results Overall, 233 patients were included. The median age was 75 years (range 64–82), 50.6% (n=118) were female, and the baseline National Institutes of Health Stroke Scale score was 8 (IQR 4–12). DMVOs were in the PCA in 59.7% (n=139) and in the ACA in 40.3% (n=94). Thrombectomy was performed under LA±CS (51.1%, n=119) and GA (48.9%, n=114). Complete reperfusion was reached in 73.9% (n=88) and 71.9% (n=82) in the LA±CS and GA groups, respectively (P=0.729). In subgroup analysis, thrombectomy for ACA DMVO favored GA over LA±CS (aOR 3.07, 95% CI 1.24 to 7.57, P=0.015). Rates of secondary and safety outcomes were similar in the LA±CS and GA groups. Conclusion LA±CS compared with GA resulted in similar reperfusion rates after thrombectomy for DMVO stroke of the ACA and PCA. GA may facilitate achieving complete reperfusion in DMVO stroke of the ACA. Safety and functional long-term outcomes were comparable in both groups.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
Alandia发布了新的文献求助10
刚刚
Qing灿发布了新的文献求助10
刚刚
淡淡蛋挞发布了新的文献求助10
1秒前
优雅苑睐完成签到,获得积分10
1秒前
1秒前
陶醉延恶发布了新的文献求助10
2秒前
2秒前
2秒前
3秒前
wanci应助大神水瓶座采纳,获得10
3秒前
1235656646发布了新的文献求助10
3秒前
3秒前
彭洪泽发布了新的文献求助10
4秒前
FashionBoy应助狮子座采纳,获得10
5秒前
思源应助动听的母鸡采纳,获得10
5秒前
5秒前
5秒前
5秒前
爆米花应助俭朴的一曲采纳,获得10
5秒前
6秒前
6秒前
嗯哼发布了新的文献求助10
6秒前
7秒前
ccc完成签到 ,获得积分10
7秒前
阿九发布了新的文献求助10
8秒前
学术学习渣子完成签到,获得积分10
8秒前
Z6kjoA发布了新的文献求助20
8秒前
彭洪泽完成签到,获得积分10
9秒前
9秒前
HAHAHA发布了新的文献求助10
9秒前
刻苦冷菱发布了新的文献求助10
9秒前
9秒前
9秒前
10秒前
1235656646完成签到,获得积分10
10秒前
tyZhang完成签到,获得积分10
10秒前
纯真冰露完成签到,获得积分10
10秒前
清爽源智完成签到,获得积分10
10秒前
xxj发布了新的文献求助30
11秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3988732
求助须知:如何正确求助?哪些是违规求助? 3531027
关于积分的说明 11252281
捐赠科研通 3269732
什么是DOI,文献DOI怎么找? 1804764
邀请新用户注册赠送积分活动 881869
科研通“疑难数据库(出版商)”最低求助积分说明 809021