Assessing and Restoring Patency in Midline Catheters

医学 导管 不利影响 溶栓药 外科 重症监护医学 内科学 溶栓 心肌梗塞
作者
Michelle L. Hawes
出处
期刊:Journal of Infusion Nursing [Ovid Technologies (Wolters Kluwer)]
卷期号:43 (4): 213-221 被引量:7
标识
DOI:10.1097/nan.0000000000000376
摘要

Maintaining and restoring patency in midline catheters has been a significant issue in the hospitalized patient requiring a multitude of infusates and frequent blood specimen collection. Currently, clinicians may not use this device as often as clinically indicated because they lack an approved intervention to treat thrombotic occlusions. The purpose of this research was to show evidence that alteplase, a US Food and Drug Administration–approved thrombolytic for central vascular access devices, is a safe and effective thrombolytic for midline catheters. A prospective open label study of 497 midline catheters was conducted from July 2018 to December 2018. Of those studied, 112 devices were treated with 1 mg of alteplase, and 109 had patency restored with 1 dose. None of the 112 patients had a major adverse event, and only 1 minor event was recorded and was resolved without removal of the midline catheter. Treating occluded central vascular access devices with 2 mg of alteplase has been safe and effective since 2001. With this research, safety and efficacy appears to be established for 1 mg of alteplase, repeat times 1 mg if necessary, in midline catheters. With the option to treat patients with occluded midline catheters rather than replace, clinicians can reduce cost, increase patient satisfaction, and preserve vein health.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI

祝大家在新的一年里科研腾飞
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
silvery发布了新的文献求助20
刚刚
3秒前
受伤11发布了新的文献求助10
3秒前
qty发布了新的文献求助30
8秒前
科研小辣机完成签到 ,获得积分10
10秒前
钟钟完成签到 ,获得积分10
15秒前
wwmmyy完成签到 ,获得积分10
16秒前
等于几都行完成签到 ,获得积分10
18秒前
汉堡包应助xxh采纳,获得10
20秒前
23秒前
25秒前
27秒前
28秒前
不鸭完成签到 ,获得积分10
28秒前
Lyensa发布了新的文献求助10
30秒前
科研通AI2S应助冰块儿采纳,获得10
30秒前
xxh发布了新的文献求助10
31秒前
伟大人物发布了新的文献求助10
32秒前
阿九发布了新的文献求助10
34秒前
qty完成签到,获得积分10
35秒前
36秒前
ding应助拼搏的思卉采纳,获得10
40秒前
42秒前
搜集达人应助沧海一粟采纳,获得10
42秒前
伟大人物发布了新的文献求助10
48秒前
50秒前
是一啵的桃桃呀完成签到,获得积分10
51秒前
53秒前
顾矜应助Moliria采纳,获得10
54秒前
Lyensa完成签到,获得积分20
54秒前
王露阳完成签到,获得积分10
56秒前
Jason完成签到 ,获得积分10
58秒前
李爱国应助乐正怡采纳,获得10
1分钟前
快乐冷风完成签到,获得积分10
1分钟前
852应助Lyensa采纳,获得10
1分钟前
dajun应助HIT_C采纳,获得30
1分钟前
1分钟前
星月完成签到 ,获得积分10
1分钟前
迷人囧完成签到 ,获得积分10
1分钟前
池鱼发布了新的文献求助10
1分钟前
高分求助中
Востребованный временем 2500
Production Logging: Theoretical and Interpretive Elements 2000
Agaricales of New Zealand 1: Pluteaceae - Entolomataceae 1500
Kidney Transplantation: Principles and Practice 1000
The moderating role of collaborative capacity in the relationship between ecological niche-fitness and innovation investment: an ecosystem perspective 800
The Restraining Hand: Captivity for Christ in China 500
The Collected Works of Jeremy Bentham: Rights, Representation, and Reform: Nonsense upon Stilts and Other Writings on the French Revolution 320
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 物理化学 催化作用 细胞生物学 免疫学 冶金
热门帖子
关注 科研通微信公众号,转发送积分 3371130
求助须知:如何正确求助?哪些是违规求助? 2989336
关于积分的说明 8735366
捐赠科研通 2672504
什么是DOI,文献DOI怎么找? 1464014
科研通“疑难数据库(出版商)”最低求助积分说明 677394
邀请新用户注册赠送积分活动 668645