In this paper, we consider an expanding flow of closed, smooth, uniformly convex hypersurface in Euclidean \mathbb{R}^{n+1} with speed u^\alpha f^\beta (\alpha, \beta\in\mathbb{R}^1), where u is support function of the hypersurface, f is a smooth, symmetric, homogenous of degree one, positive function of the principal curvature radii of the hypersurface. If \alpha \leq 0<\beta\leq 1-\alpha, we prove that the flow has a unique smooth and uniformly convex solution for all time, and converges smoothly after normalization, to a round sphere centered at the origin.