Mechanochemical synthesis of MOFs

Metal-organic frameworks (MOFs) possess a wide variety of potential applications in chemistry, biomedical engineering, and pharmaceutical fields. Systematic combinations of metal and organic components enable an unprecedented rational design of framework structures for each application. Of great importance to translating MOFs into practical technologies is the ability to manufacture MOFs with the scale, purity, and cost required for implementation. Mechanochemistry is a promising way for large-scale and environmentally friendly material synthesis employed in various areas of synthetic chemistry. This short review discusses the up-to-date developments, challenges, and opportunities of mechanochemistry for MOFs synthesis.