Wnt信号通路
椎间盘
变性(医学)
连环蛋白
连环素
细胞生物学
病理
信号转导
医学
生物
解剖
作者
Jingbo Kong,Xinlong Ma,Tao Wang,Jianxiong Ma,Peng Tian,Chao Han,Jiacheng Zang,Pengfei Li,Hongqiang Jiang
出处
期刊:PubMed
日期:2013-12-01
卷期号:27 (12): 1523-8
被引量:8
摘要
To review the progress of the mechanisms of Wnt/beta-catenin and nuclear factor-kappa B (NF-kappaB) pathways in the process of the intervertebral disc degeneration.The related literature about the mechanisms of Wnt/beta-catenin and NF-kappaB pathways in the process of the intervertebral disc degeneration was reviewed, analyzed, and summarized.Wnt/beta-catenin and NF-kappaB pathways are both activated in the process of the intervertebral disc degeneration, and exist interaction. However, the specific mechanisms and interactive mediums of Wnt/beta-catenin and NF-kappaB pathways in the process of the intervertebral disc degeneration are still unclear.The mechanisms of Wnt/beta-catenin and NF-kappaB pathways in the process of the intervertebral disc degeneration have to be studied deeply.
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