[Experience in the use of bronchofibroscopy in the treatment for acute lung injury after liver transplantation].

医学 急性呼吸窘迫综合征 肝移植 机械通风 重症监护室 麻醉 氧合指数 充氧 动脉血 移植 存活率 外科 内科学
作者
Wan‐Ping Chen,Qifa Ye,Ke Li,Qi-Quan Wan,Ying Ma
出处
期刊:PubMed 卷期号:20 (5): 264-7 被引量:1
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摘要

To evaluate retrospectively the clinical therapeutic effects of the application of bronchofibroscopy(BFS) in the treatment of acute lung injury (ALI) after liver transplantation.Fifty-eight patients with ALI caused by various kinds of reasons after liver transplantation were divided into two groups depending on whether the BFS was undertaken (group A, n=36) or not (group B, n=22), and the clinical therapeutic effects were evaluated by comparing the length of intensive care unit (ICU) stay and mechanical ventilation, mortality rate of ALI, morbidity and mortality rate of acute respiratory distress syndrome (ARDS) and changes in arterial blood gas analysis before and after BFS treatment.The length of ICU stay [(11+/-4) days vs. (16+/-4) days] and mechanical ventilation [(9+/-5) days vs. (14+/-5) days, both P<0.01] in group A were shorter, and mortality rate of ALI (11.1% vs. 36.4%), morbidity rate (27.8% vs. 54.5%, P<0.05 and P<0.01) and mortality rate of ARDS [40.0% (4/10) vs. 66.7% (8/12)] were lower in group A compared with group B (P>0.05). Arterial partial pressure of oxygen (PaO(2)), partial pressure of carbon dioxide (PaCO(2)), arterial oxygen saturation (SaO(2)), and oxygenation index (PaO(2)/FiO(2)) after treatment were much better than those before BFS in group A and the differences were significant (all P<0.01).BFS is a kind of safe and effective treatment measure for ALI after liver transplantation and is worthwhile to recommend.

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