Modified-Single Patch vs Double Patch Repair of Complete Atrioventricular Septal Defects

医学 四分位间距 累积发病率 外科 房室瓣 回顾性队列研究 房室间隔缺损 入射(几何) 内科学 心脏病学 移植 心脏病 光学 物理 心室
作者
Laura S. Fong,Kim Betts,Raviteja Kannekanti,Julian Ayer,David S. Winlaw,Yishay Orr
出处
期刊:Seminars in Thoracic and Cardiovascular Surgery [Elsevier BV]
卷期号:32 (1): 108-116 被引量:6
标识
DOI:10.1053/j.semtcvs.2019.07.004
摘要

Biventricular repair of complete atrioventricular septal defect (CAVSD) is largely achieved using the double-patch (DP) or modified single-patch (MSP) techniques in the current era; however, long-term results following MSP repair are not well defined. We aimed to compare long-term outcomes including reoperation and mortality after CAVSD repair using DP and MSP techniques, and identify the risk factors associated with adverse outcomes. A retrospective cohort study was performed including all patients who underwent CAVSD repair using DP and MSP techniques at our institution between 17 May 1990 and 14 December 2015. Demographic details, early (≤30 days) and late (>30 days) outcomes (reoperation, mortality) were studied. Competing risks analysis with cumulative incidence function was used for survival analyses. Overall, 273 consecutive patients underwent CAVSD repair (120 DP and 153 MSP) and 41 patients required reoperation during follow-up. Competing risks analysis showed no association between repair technique and reoperation (P = 1.0) or mortality (P = 0.9). Considering competing risks due to mortality, the cumulative incidence of reoperation at 5, 10, and 15 years was 14%, 17%, and 17% for DP and 12%, 13%, and 16% for MSP, respectively. Non-Down syndrome and moderate or greater left atrioventricular valve regurgitation were predictors for reoperation. Pulmonary artery banding was predictive of mortality, though strongly associated with earlier surgical era. Median follow-up duration was 8.0 years (interquartile range 3.9–20.8) for DP and 11.6 years (interquartile range 5.4–16.1) for MSP (P = 0.4). Event-free survival is similar after DP and MSP repair of CAVSD indicating either repair technique can be safely utilized. Biventricular repair of complete atrioventricular septal defect (CAVSD) is largely achieved using the double-patch (DP) or modified single-patch (MSP) techniques in the current era; however, long-term results following MSP repair are not well defined. We aimed to compare long-term outcomes including reoperation and mortality after CAVSD repair using DP and MSP techniques, and identify the risk factors associated with adverse outcomes. A retrospective cohort study was performed including all patients who underwent CAVSD repair using DP and MSP techniques at our institution between 17 May 1990 and 14 December 2015. Demographic details, early (≤30 days) and late (>30 days) outcomes (reoperation, mortality) were studied. Competing risks analysis with cumulative incidence function was used for survival analyses. Overall, 273 consecutive patients underwent CAVSD repair (120 DP and 153 MSP) and 41 patients required reoperation during follow-up. Competing risks analysis showed no association between repair technique and reoperation (P = 1.0) or mortality (P = 0.9). Considering competing risks due to mortality, the cumulative incidence of reoperation at 5, 10, and 15 years was 14%, 17%, and 17% for DP and 12%, 13%, and 16% for MSP, respectively. Non-Down syndrome and moderate or greater left atrioventricular valve regurgitation were predictors for reoperation. Pulmonary artery banding was predictive of mortality, though strongly associated with earlier surgical era. Median follow-up duration was 8.0 years (interquartile range 3.9–20.8) for DP and 11.6 years (interquartile range 5.4–16.1) for MSP (P = 0.4). Event-free survival is similar after DP and MSP repair of CAVSD indicating either repair technique can be safely utilized. Commentary: Complete Atrioventricular Canal Defects: Is There a Superior Repair Technique?Seminars in Thoracic and Cardiovascular SurgeryVol. 32Issue 1PreviewThe article by Fong et al in this issue of Seminars provides a commendable retrospective analysis of complete atrioventricular canal defect (AVCD) repairs over a 25-year period at their institution.1 All patients included in the study received either a modified single-patch or double-patch repair technique. The authors should be applauded for the lengthy follow-up of their patients in the modified single-patch group. Full-Text PDF

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