Modified-Single Patch vs Double Patch Repair of Complete Atrioventricular Septal Defects

医学 四分位间距 累积发病率 外科 房室瓣 回顾性队列研究 房室间隔缺损 入射(几何) 内科学 心脏病学 移植 心脏病 光学 物理 心室
作者
Laura S. Fong,Kim Betts,Raviteja Kannekanti,Julian Ayer,David S. Winlaw,Yishay Orr
出处
期刊:Seminars in Thoracic and Cardiovascular Surgery [Elsevier]
卷期号:32 (1): 108-116 被引量:6
标识
DOI:10.1053/j.semtcvs.2019.07.004
摘要

Biventricular repair of complete atrioventricular septal defect (CAVSD) is largely achieved using the double-patch (DP) or modified single-patch (MSP) techniques in the current era; however, long-term results following MSP repair are not well defined. We aimed to compare long-term outcomes including reoperation and mortality after CAVSD repair using DP and MSP techniques, and identify the risk factors associated with adverse outcomes. A retrospective cohort study was performed including all patients who underwent CAVSD repair using DP and MSP techniques at our institution between 17 May 1990 and 14 December 2015. Demographic details, early (≤30 days) and late (>30 days) outcomes (reoperation, mortality) were studied. Competing risks analysis with cumulative incidence function was used for survival analyses. Overall, 273 consecutive patients underwent CAVSD repair (120 DP and 153 MSP) and 41 patients required reoperation during follow-up. Competing risks analysis showed no association between repair technique and reoperation (P = 1.0) or mortality (P = 0.9). Considering competing risks due to mortality, the cumulative incidence of reoperation at 5, 10, and 15 years was 14%, 17%, and 17% for DP and 12%, 13%, and 16% for MSP, respectively. Non-Down syndrome and moderate or greater left atrioventricular valve regurgitation were predictors for reoperation. Pulmonary artery banding was predictive of mortality, though strongly associated with earlier surgical era. Median follow-up duration was 8.0 years (interquartile range 3.9–20.8) for DP and 11.6 years (interquartile range 5.4–16.1) for MSP (P = 0.4). Event-free survival is similar after DP and MSP repair of CAVSD indicating either repair technique can be safely utilized. Biventricular repair of complete atrioventricular septal defect (CAVSD) is largely achieved using the double-patch (DP) or modified single-patch (MSP) techniques in the current era; however, long-term results following MSP repair are not well defined. We aimed to compare long-term outcomes including reoperation and mortality after CAVSD repair using DP and MSP techniques, and identify the risk factors associated with adverse outcomes. A retrospective cohort study was performed including all patients who underwent CAVSD repair using DP and MSP techniques at our institution between 17 May 1990 and 14 December 2015. Demographic details, early (≤30 days) and late (>30 days) outcomes (reoperation, mortality) were studied. Competing risks analysis with cumulative incidence function was used for survival analyses. Overall, 273 consecutive patients underwent CAVSD repair (120 DP and 153 MSP) and 41 patients required reoperation during follow-up. Competing risks analysis showed no association between repair technique and reoperation (P = 1.0) or mortality (P = 0.9). Considering competing risks due to mortality, the cumulative incidence of reoperation at 5, 10, and 15 years was 14%, 17%, and 17% for DP and 12%, 13%, and 16% for MSP, respectively. Non-Down syndrome and moderate or greater left atrioventricular valve regurgitation were predictors for reoperation. Pulmonary artery banding was predictive of mortality, though strongly associated with earlier surgical era. Median follow-up duration was 8.0 years (interquartile range 3.9–20.8) for DP and 11.6 years (interquartile range 5.4–16.1) for MSP (P = 0.4). Event-free survival is similar after DP and MSP repair of CAVSD indicating either repair technique can be safely utilized. Commentary: Complete Atrioventricular Canal Defects: Is There a Superior Repair Technique?Seminars in Thoracic and Cardiovascular SurgeryVol. 32Issue 1PreviewThe article by Fong et al in this issue of Seminars provides a commendable retrospective analysis of complete atrioventricular canal defect (AVCD) repairs over a 25-year period at their institution.1 All patients included in the study received either a modified single-patch or double-patch repair technique. The authors should be applauded for the lengthy follow-up of their patients in the modified single-patch group. Full-Text PDF

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
1秒前
1秒前
从容迎夏发布了新的文献求助10
1秒前
13发布了新的文献求助10
1秒前
小帅完成签到,获得积分10
1秒前
kohu发布了新的文献求助30
2秒前
2秒前
天黑黑发布了新的文献求助10
2秒前
思源应助鲸鱼采纳,获得10
2秒前
2秒前
我是老大应助zyzy1996采纳,获得10
2秒前
3秒前
3秒前
bing完成签到 ,获得积分10
3秒前
3秒前
4秒前
yejian完成签到,获得积分10
4秒前
冷酷的天晴完成签到 ,获得积分10
4秒前
张亚宁完成签到,获得积分20
4秒前
吃不下发布了新的文献求助10
4秒前
4秒前
4秒前
大模型应助小宇宙ZKYYS采纳,获得10
5秒前
5秒前
5秒前
滚滚完成签到,获得积分10
5秒前
6秒前
6秒前
6秒前
6秒前
6秒前
582697438完成签到,获得积分20
7秒前
dudu发布了新的文献求助10
7秒前
可爱的函函应助小Q采纳,获得10
7秒前
xuening完成签到,获得积分10
8秒前
8秒前
开心听露发布了新的文献求助10
8秒前
情怀应助陈泽宇采纳,获得10
9秒前
哈哈发布了新的文献求助10
9秒前
高分求助中
(应助此贴封号)【重要!!请各用户(尤其是新用户)详细阅读】【科研通的精品贴汇总】 10000
Translanguaging in Action in English-Medium Classrooms: A Resource Book for Teachers 700
Exploring Nostalgia 500
Natural Product Extraction: Principles and Applications 500
Exosomes Pipeline Insight, 2025 500
Qualitative Data Analysis with NVivo By Jenine Beekhuyzen, Pat Bazeley · 2024 500
Advanced Memory Technology: Functional Materials and Devices 400
热门求助领域 (近24小时)
化学 材料科学 生物 医学 工程类 计算机科学 有机化学 物理 生物化学 纳米技术 复合材料 内科学 化学工程 人工智能 催化作用 遗传学 数学 基因 量子力学 物理化学
热门帖子
关注 科研通微信公众号,转发送积分 5667995
求助须知:如何正确求助?哪些是违规求助? 4888874
关于积分的说明 15122780
捐赠科研通 4826840
什么是DOI,文献DOI怎么找? 2584376
邀请新用户注册赠送积分活动 1538211
关于科研通互助平台的介绍 1496526