[Study on the preparation of sustained-release pellets containing active components from Gastrodia elata by fluid-bed coating].

To study the formulation of sustained-release pellets containing active components from Gastrodia elata by coating in the fluid-bed.The sustained-release pellets were prepared with Eudragit RS 100. The formulation was optimized by the direct comparison. Then their properties were evaluated.The pellets presented the perfect sphericity and narrow diameter distribution and the curve of their cumulative drug release was in accord with Higuchi equation.The pellets have sustained-release effect in 12 hours.