Condyloma acuminatum is a benign, sexually transmitted papillary lesion, primarily found in the anogenital region. Although reports of oral condyloma acuminatum are appearing more frequently, they still are sparse. The lesion is caused by the Papova virus and the differentiation from other papular growths of the oral cavity is often difficult. In the present study two histologically documented cases of the lesion are presented and the clinicopathologic features of all cases with oral involvement reported in the literature are analyzed.