Structural Modifications that Alter the P-Glycoprotein Efflux Properties of Compounds

ADVERTISEMENT RETURN TO ISSUEPerspectiveNEXTStructural Modifications that Alter the P-Glycoprotein Efflux Properties of CompoundsStephen A. Hitchcock†View Author Information Envoy Therapeutics, 555 Heritage Drive, Jupiter Florida 33458, United States†Phone: (561) 210-7705. E-mail: [email protected]Cite this: J. Med. Chem. 2012, 55, 11, 4877–4895Publication Date (Web):April 16, 2012Publication History Received24 August 2011Published online16 April 2012Published inissue 14 June 2012https://pubs.acs.org/doi/10.1021/jm201136zhttps://doi.org/10.1021/jm201136zreview-articleACS PublicationsCopyright © 2012 American Chemical SocietyRequest reuse permissionsArticle Views11587Altmetric-Citations172LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Antibiotic resistance,Central nervous system,Peptides and proteins,Permeability,Rodent models Get e-Alerts